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Symbol
Name
ID

Esr1
estrogen receptor 1 (alpha)
MGI:1352467

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Photophobia	Phonophobia	Migraine with aura	Migraine without aura
Disease(s) Associated with ESR1
migraine

Mouse Phenotypes		nervous system phenotype	decreased gonadotroph cell number	increased gonadotroph cell number	decreased lactotroph cell number	abnormal pituitary gland physiology	abnormal hypothalamus morphology	abnormal innervation
Availability	Mouse Genotype	nervous system phenotype	decreased gonadotroph cell number	increased gonadotroph cell number	decreased lactotroph cell number	abnormal pituitary gland physiology	abnormal hypothalamus morphology	abnormal innervation
	Esr1^tm1Ksk/Esr1^tm1Ksk
	Esr1^tm1.2Awo/Esr1^tm1.2Awo Tg(Cga-cre)1Awo/0 (conditional)
	Esr1^tm1.2Mma/Esr1^tm1.2Mma Tg(Cyp17a1-icre)AJako/0 (conditional)
	Esr1^tm1Gsc/Esr1^tm1Gsc Tg(Camk2a-cre)2Gsc/0 (conditional)	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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